First post on this site, so go easy on me.
I'll share a personal experience that occurred recently to me. I had (sold it to get an 05) a 02 Pro, and it suddenly developed a severe off idle hesitation that it never had before. The hesitation would occur when attempting heavy throttle/clutch slipping areas, such as a rock face. I went down the whole list.....carb clean, jetting, changed the petcock, cleaned the tank, checked the reeds, checked compression, air filter, exhaust sealing, etc etc. I was baffled until I remembered to go back and recheck for anything I may have overlooked. That's when I remembered when cleaning up in the garage I had come across a few brand new non-resistor plugs that were identical to what was in the bike...except for the fact of being non resistor (BP5ES I believe). I didn't think it would have any effect, but I put a resistor plug back in the bike. It was actually the old one I had taken out to begin with. If it wasn't my own experience in dealing with the whole issue, I myself wouldn't believe it would have such an effect. The off idle hesitation was gone. I thought that perhaps the suspect non resistor plug may have been fouled, so I put in another brand new non resistor plug. Hesitation returns. Put back the old resistor plug, bike ran excellent.
If I tried to technically explain why it had such an adverse effect, I'd be making it up. I don't know, but I would have to believe it would have to be along the lines of ignition interference with the engine under load. So for what it's worth, in my own personal experience, I would say it does have an effect when using a non resistor plug. You may just not notice it based on how and where you ride.