Some dealers back in the day took 125/175/250 Bultacos out to 325 using a new liner but it was a hec of a lot of work - press out the old liner, bore cylinder to take new 325 liner, open up the transfer ducts, split the cases to enlarge the crankcase 'mouth' for the new liner, machine head & combustion chamber adjusting dia & C.R. to suit larger capacity, then fit bushes on the 16mm gudgeon pin (of the smaller engines) to take the 325 piston (which used 20mm pin).
Bert Flood sold the kits in Australia & a local rider had it done on his Sherpa S 125 by our local dealer. But it always seemed a somewhat less than satisfactory practice to me, especially bushing the 16mm pin to take the 83mm piston. And if you didn't get the transfer ducts and head mods right....
These days guys seem to prefer boring out the 250 to take 76mm GasGas piston, giving extra 28cc. Don't know if they just bore the std liner or make new one. The Bul 250 liners are 4mm thick so that would only leave a 2mm thick liner if they just bored the liner. For me that'd be right on the limit. Don't know if the deck ht is correct or if you need to run a reedvalve with the GG piston either (ie if there's holes in the skirt.)
Another idea I've toyed with but never fully investigated is to use a 75mm KawJS550 watercraft piston, up to 1990 model which were pistonport engines (later models were reedvalve). Wiseco list them as having 16mm gudgeon, same as 250 Bul, but don't know if deck ht or ring locating pins are suitable. That'd give 21cc extra & more meat in the liner